Model and applied research organisms are valuable for comparative genomics research, evolutionary biology, and continue to play a critical role in deciphering the molecular mechanisms underlying human disease, and agricultural crop improvement. Affymetrix® Gene 1.1 ST Array Strips have been developed for the analysis of a wide range of model and applied research organisms. These organisms are the latest additions to the growing family of Affymetrix® Gene Expression Microarrays offering whole-transcript coverage. The Affymetrix® Gene 1.1 ST Array Strip were designed in collaboration with influential researchers, such as Alan Archibald, Head of the Division of Genetics and Genomics at the Roslin Institute (Porcine Gene 1.1 ST array design), Leonard Zon, Director of Stem Cell Research Program, and Yi Zhou, Genomic Core Director of the Stem Cell Research Program at Children's Hospital Boston and Harvard Medical School in Boston (Zebrafish Gene 1.1 ST Array design).

Key benefits

• Highest transcript coverage – get confident expression measurements of well-annotated content with up to 26 probes per transcript
• Whole-transcriptome analysis – capture the transcript isoforms you may miss with 3'-biased expression designs
• High data correlation – achieve high inter- and intra-array strip signal correlation (R >0.99)
• Convenient format – process four samples at the same time with minimal manual array handling
• Simple workflow – streamline your work, from target preparation through pathway analysis, and use intuitive software for data interpretation

Proven performance from the industry standard

Array Strips		Affymetrix Gene 1.1 ST Array Strips offer whole–transcriptome coverage for selected model and applied research organisms. All designs are based on the most recent genomic content and offer the highest probe coverage (up to 26 probes across the full length of the gene). This allows for accurate detection for whole-transcriptome microarray analysis and provides higher resolution and accuracy than other classical 3'-biased microarray solutions on the market. The whole-transcriptome analysis approach enables researchers to detect multiple transcript isoforms, including those that might be missed using a 3'-biased expression design, such as splice variants, non-polyadenylated transcripts, transcripts with alternative polyadenylation sites, and truncated transcripts.
Array Comparison		Affymetrix Gene 1.1 ST Array Strips are designed exclusively for the GeneAtlas® System—the first personal microarray system to allow four samples to be processed in parallel. It combines affordability, simplified workflow, ease of use, intuitive software, and excellent performance. For more information on the GeneAtlas System, please visit www.affymetrix.com/geneatlas. Affymetrix Gene 1.1 ST Array Strips are supported by our easy-to-use and integrated data analysis software pipeline, which includes GeneAtlas® Instrument Control Software for instrument processing of array strips, Partek® Express™ Software for quality control and statistical analysis, and Ariadne Pathway Studio® Explore Software for pathway analysis, visualization, and other features that allow you to put your data into a biological context.
Please note that Pathway Studio Explore includes the ResNet® Mammalian Database, which supports analysis of human, mouse, and rat sequences. The software also offers access to the ResNet® Plant Database, which has gene definitions from Entrez for Arabidopsis, rice, and soybean, but other than Arabidopsis, only has relationship data for those species-specific genes. You may contact Ariadne to obtain the ResNet Plant Database on DVD free of charge. For all other organisms, contact Ariadne to explore possibilities for creating a custom database.

Gene 1.1 ST Array Strips enable you to:

• Measure expression, across the entire gene, with higher resolution and accuracy than with classical 3'-biased microarray solutions
• Get accurate and reproducible data by using multiple independent measurements for each transcript
• Process four samples on a single array strip with the cost-effective GeneAtlas System

Array strip content source (view table)		Content profile Gene 1.1 ST Array Strips provide the latest coverage of the transcribed genome. We use a comprehensive collection of information sources to design probes that interrogate up to 26 unique sequences of each transcript. Together these 26 unique 25-mer probes interrogate up to 650 bases per transcript. This high probe coverage across the entire transcript results in superior performance and data confidence as well as the ability to update your experimental data as the understanding of each genome and transcriptome grows.
"For Research Use Only. Not for use in diagnostic procedures."